to compare the efficacy of propofol with ketamine versus propofol with fentanyl for procedural sedation for patients undergoing endoscopic retrograde cholangiopancreatography

Objective: This study was conducted to compare the efficacy of Propofol with Ketamine versus Fentanyl for procedural sedation patients undergoing ERCP evaluate consumption, recovery score, patient satisfaction and related adverse events. Materials Methods: Sixty aged 18-60 years, ASA Class I II were randomly allocated one two groups; Propofol/Ketamine (Ketofol) group KP (n=30) Propofol/Fentanyl FP (n=30). The level adjusted achieve a Ramsay Sedation Scale (RSS) score 5. Results: total amount consumed significantly higher in (109.883±11.3871 mg) compared (89.867±9.8942 mg). Time reach acceptable slightly longer (Aldrete scores 9.5±0.509, 9.8±0.407 respectively at 30 min). Patient comparable both groups side effects like hypotension, bradycardia, desaturation more significant group. Conclusion: Propofol-Ketamine combination provided quality similar Propofol-Fentanyl better hemodynamic profile fewer effects. Hence can be safely used ERCP.